Viramune | Nevirapine
This medication is used in the management of infection with the HIV virus (the virus that causes AIDS). It is used in grouping with other HIV medications in selected patients. No cure survive for HIV infection, and the illnesses associated with your disease (infections, etc.) may continue. Because HIV can rapidly become resistant to this medication if used alone, viramune must be used with at least 1 other anti-HIV medications. Your doctor may vary your treatment plan if this medication stops working well.
How Taken
Take by mouth as directed. The usual dose is one 200 mg tablet daily for the first 14 days, and then followed by one 200 mg tablet twice a day. Viramune is in use with at least one other medication (antiretroviral) for HIV. It is vital to follow the dosing instructions carefully in order to minimize serious side effects, such as rash. If a rash develops in the first two weeks, the viramune dose is not increased until the rash is gone. If treatment is blocked for more than 7 days, then re-treatment should begin as directed by your doctor, usually with one 200 mg tablet daily for 14 days, then one 200 mg tablet twice a day. Read the Patient Information Leaflet accessible from your pharmacist. If you have any questions, consult your doctor or pharmacist.
Drug Class and Mechanism
Viramune is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is like to efavirenz (Sustiva) and delavirdine (Rescriptor). Viramune is in a class of drugs termed reverse transcriptase inhibitors which includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), and lamivudine (Epivir). During infection with HIV, the HIV virus grows within the body’s cells. The newly-formed viruses then are unrestricted from the cells and spread throughout the body where they infect other cells. In this method, the infection spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When creating new viruses, the HIV virus must manufacture new DNA for each virus. Annul transcriptase is the enzyme that the virus uses to form this new DNA. Viramune openly inhibits the activity of reverse transcriptase and blocks the production of DNA and new viruses. Unlike zidovudine, nevirapine does not need to be converted to an active form and it does not compete with the compound (thymidine triphosphate) that is required by HIV virus to make new DNA. Viramune does not kill existing HIV virus and it is not a cure for HIV.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is within 2 hours of the next dose, skip the missed dose and resume your usual dosing schedule. It is important not to miss doses of this drug.
Storage
Keep the medication at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from moisture and light as directed. Do not store in the bathroom. Keep in a tightly closed bottle.
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